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Referências

Referências Bibliográficas

  1. 1. Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease: meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73-84.
  2. 2. European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD), European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease. J Hepatol. 2016;64(6):1388-402.
  3. 3. Israelsen M, Francque S, Tsochatzis EA, Krag A. Steatotic liver disease. Lancet. 2024;404(10464):1761-1778.
  4. 4. Singh S, Allen AM, Wang Z, Prokop LJ, Murad MH, Loomba R. Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-analysis of paired-biopsy studies. Clin Gastroenterol Hepatol. 2015;13(4):643-654.e1-9.
  5. 5. Mofrad P, Contos MJ, Haque M, Sargeant C, Fisher RA, Luketic VA, et al. Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values. Hepatology. 2003;37(6):1286-1292.
  6. 6. Fracanzani AL, Valenti L, Bugianesi E, Andreoletti M, Colli A, Vanni E, et al. Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: a role for insulin resistance and diabetes. Hepatology. 2008;48(3):792-798.
  7. 7. Prevalência global - 1 em cada 3
    Younossi ZM et al. The global epidemiology of NAFLD and NASH: a systematic review. Hepatology, 2023.
    https://pubmed.ncbi.nlm.nih.gov/36062860/
  8. 8. Prevalência global atualizada
    High global prevalence of steatotic liver disease: a meta-analysis. Clinical Gastroenterology and Hepatology, 2025.
    https://www.cghjournal.org/article/S1542-3565(25)00242-3/fulltext
  9. 9. Cirrose - principal causa nos países ocidentais
    Huang DQ et al. Global epidemiology of cirrhosis - aetiology, trends and predictions. Nature Reviews Gastroenterology & Hepatology, 2023.
    https://www.nature.com/articles/s41575-023-00759-2
  10. 10. Burden hepático no Brasil - segunda causa
    Burden of liver disease in Brazil, 1996-2022. The Lancet Regional Health - Americas, 2024.
    https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(24)00058-9/fulltext
  11. 11. Diretriz brasileira oficial - SBH / SBEM / Abeso
    Moreira RO et al. Brazilian evidence-based guideline for screening, diagnosis, treatment, and follow-up of MASLD.